I eventually put the 160 in my MKS. I monitored engine temps with an Aeroforce gauge both with the stock thermostat and the 160. Once the car had been driven and the temps reached their maximum, there was NO difference whatsoever in running temperatures. Just cruising on the highway, both ran 185-190. The 160 took a bit longer to reach maximum temp since it opened sooner but once fully open, there was no difference between the two.
I had Livernois leave the fan settings alone for my daily driver tune but had a tune for drag racing in which the fans came on at a lower temp. At the drag strip, the car did cool down more rapidly after a run with the 160 but I suspect the fans kicking on sooner had a lot to do with that. With either thermostat, I would see 215+ degrees at the end of the quarter mile.
The 2010-2012 MKS had a larger lower grill opening than an SHO so that might make some difference, too.