On a stock system, no exhaust work, you should be able to have the rear O2's on with no CEL. The front O2 sensors monitor the air/fuel ratio and are the feedback loop for the system. The rear O2's don't impact performance and simply monitor the status of the catalytic converters.
If you go with catless downpipes or sometimes high flow catted downpipes they won't be efficient enough and the stock system will throw a rear O2 CEL because the cats aren't cleaning the exhaust enough for stock. So you can either run with a CEL for rear O2's or have the tuner turn them off. Most turn them off so if the engine throws a different CEL they will know to check it.