Can you fill us in on the maintenance history on this SHO, Jason? Pretty much everything is due at this mileage. Spark plugs, transmission fluid, PTU/RDU fluid, coolant, etc. You feel the issue has become worse with the new turbos? Why were new turbos installed? Some sort of seal leak, or ...?
Could be chafing knock sensor wires, an issue mostly confined to 2010-12, but sometimes occurs on the 2013+ also.
Could be torque converter shudder, if load is constant, but rpms fluctuate on their own.
Could be the PTU, check for fluid leaks from the vent, and from the seals between PTU/transmission & PTU/axle.
Hopefully just the plugs need changing out ...