You can buy the tuner/tune before any upgrades, just let Unleashed know what your current mods are, and keep them informed of mods you make so the tune(s) can be updated to accommodate. If your SHO goes in for service, and for some reason the strategy code is updated, you have to let them know as well, because you will need an updated tune to load to the PCM afterwards.
TStat can be done without tune, but a tune turns on the fans earlier so you can take full advantage of the TStat. 3bar NEEDS a tune to work correctly, as the mapping tables from the factory are for a 2 bar MAP.
Reliability has not been an issue with Unleashed.